ABSTRACT
Objective:To investigate the clinical significance of epidermal growth factor receptor(EGFR),proliferating cell nuclear antigen(PCNA),laminin(LN)and type IV collagen expression in salivary adenoid cystic carcinoma(SACC).Methods:EGFR gene in 78 cases of SACC with complete clinical data was detected by fluorescence in situ hybridization(FISH)technique,the expression of EGFR,PCNA,LN and type IV collagen protein was detected by immunohistochemistry technique(IHC),their correlation with the clin-icopathological parameters was analysed by SPSS 13.00 software.Results:EGFR gene amplification levels(69.2%)was positively related to the ratio of EGFR protein positive expression(7 1 .8%),the expression of EGFR,PCNA,LN and type IV collagen was posi-tively related to the clinical pathological parameters(P<0.05).There was a positive correlation between EGFR and PCNA expression (P<0.05),a negative correlation between LN protein and type IV collagen protein expression(P<0.05).Conclusion:EGFR gene is amplified in SACC.EGFR,PCNA,LN and type IV collagen take part in the occurrence and development of SACC.
ABSTRACT
Objective To study the effect of clinical nursing pathway on oral and maxillofacial trauma.Methods One hundred inpatients were assigned according to the odd or even number of registration into the experiment group and the control group equally.The experiment group received clinical nursing pathway while the control one routine nursing.Results The rates of awareness of health education and satisfaction in the experiment group were significantly higher than the control group and the average stay was significantly shorter than that of the control group(both P<0.05).Conclusion The clinical nursing pathway used in the care of oral and maxillofacial trauma may standardize the manipulations of nursing care,enhance the nursing staff's sense of responsibility, and promote the patients' satisfaction,as well as the quality of care.